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Outlaw Jesse James is rumored to be the 'fastest gun in the West'. An eager recruit into James' notorious gang, Robert Ford eventually grows jealous of the famed outlaw and, when Robert and his brother sense an opportunity to kill James, their murderous action elevates their target to near mythical status.

Dr. Frankenstein's Granddaughter Maria, and her brother assistant Rudolph, moved to the old west because the lightning storms there are more frequent and intense, which allows them to work on the experiments of their grandfather. But the experiments are failing and Rudolph's been secretly killing the corpses afterwards. Meanwhile, the Lopez family leaves the town because of the evil going on there

Frank James resents and tries to stop a ruthless drifter who has adopted the name of his dead brother in order to duplicate his crimes.

The gangs of Jesse James and Cole Younger join forces to rob the First National Bank in Northfield, Minnesota, but things do not go as planned.

Bob Ford murders his best friend Jesse James in order to obtain a pardon that will free him to marry his girlfriend Cynthy. The guilt-stricken Ford soon finds himself greeted with derision and open mockery throughout town. He travels to Colorado to try his hand at prospecting in hopes that marriage with Cynthy is still in the cards.

Farmer Frank and his ward hunt brother Jesse's killers, the back-shooting Fords.

After railroad agents forcibly evict the James family from their family farm, Jesse and Frank turn to banditry for revenge.

At the end of the Civil War, Frank and Jesse James and other former guerillas who rode with Quantrill and Bill Anderson take the oath of allegiance to the Union. Feeling oppressed by Chicago railroad investors, the James and Younger brothers, Bob and Charlie Ford, Clell Miller and Arch Clements take to robbing banks, trains and coaches, with Pinkerton sworn to bringing them to justice.

The origins, exploits and the ultimate fate of the James gang is told in a sympathetic portrayal of the bank robbers made up of brothers who begin their legendary bank raids because of revenge.

When a Midwest town learns that a corrupt railroad baron has captured the deeds to their homesteads without their knowledge, a group of young ranchers join forces to take back what is rightfully theirs. They will become the object of the biggest manhunt in the history of the Old West and, as their fame grows, so will the legend of their leader, a young outlaw by the name of Jesse James.

After some gun play with a posse, the James Gang head for Quinto in a section of land which is not a part of America. Anyone there is beyond the law so the town is populated with outlaws. Next to arrive is Sheriff Rowley, following his brother whom the Gang have brought in injured. Rowley has no authority and gets on well enough with the James boys but is soon involved in other local goings-on, including a move to vote for annexation with Oklahoma which would allow the law well and truly in.